Au lodi r, schapira ah, manners d, styles p, wood nw, taylor dj, warner tt so. Huntingtons disease and laboratory investigation of this disease. References for huntingtons disease cite this for me. Researchers have developed a novel measure of disease progression for huntingtons disease, which enabled them to identify a genetic modifier associated with how rapidly the disease progresses.
This book is a vital resource for learning more about heart disease and preventative care regarding heart health. As the disease advances, uncoordinated, jerky body movements become more apparent. Further it has information regarding the treatment and prevention. Although members of huntingtons disease families will find some chapters to be. If you read george huntingtons original paper on the disease from back in 1872, his description of the condition remains pretty much spot on as to how the disease is described today. Novel regulator inhibits toxic protein aggregates in huntingtons disease. Research paper on huntingtons disease 10 october 2016 huntingtons disease is a hereditary brain disorder that is progressive in neurodegeneration. An additional eight articles were identified from reference lists and. Huntington s disease offers introduces this disease, detailing its history and progression, and discusses the search for the gene that causes it and the development of genetic tests for the gene.
Essay huntingtons disease huntingtons disease, or huntngtons chorea, is a genetic disease that causes selective neural cell death, which results in chorea, or irregular, jerking movements of the limbs caused by involuntary muscle contractions, and dementia. For a complete list of how to cite print sources, please refer to the 7 th edition of the apa. Huntingtons disease is an inherited disease that causes the progressive breakdown degeneration of nerve cells in the brain. Psychiatric disorders in preclinical huntingtons disease.
Typically, onset of symptoms is in middleage after affected individuals have had children, but the disorder can manifest at any time between infancy and senescence. Huntingtons disease hd is a fatal progressive neurodegenerative disorder that was named after dr. Genetics home reference is a consumer health website from the national library of medicine, which is part of the national institutes of health, an agency of the u. How you cite a cdc report will differ based on whether it is a web or print document. Select a disorder disease state that is a result of a genetic alteration. It can cause a lack of concentration and depression. Huntingtons disease is an inherited neurodegenerative disorder that usually emerges in. Worldwide, huntingtons disease affects between 37 per 100,000 people of european ancestry schoenstadt. Dec 18, 2006 psychiatric symptoms are a common feature of huntington s disease hd and often precede the onset of motor and cognitive impairments.
Digital book index provides links to several thousand books at hundreds of sites including gutenberg. Citation machine helps students and professionals properly credit the information that they use. The paper should be no more than 3 pages excluding title page and references. Huntington disease is a progressive brain disorder that causes uncontrolled movements, emotional problems, and loss of thinking ability cognition adultonset huntington disease, the most common form of this disorder, usually appears in a persons thirties or forties. Food and huntingtons disease is another book in a series of books related to the benefits of food on brain function. Medline abstract for reference 63 of huntington disease. Exercise and the heart in health and disease presents information about exercise and how it relates to both disease and.
Adultonset huntington disease, the most common form of this disorder, usually appears in a persons thirties or forties. May 04, 2017 in huntingtons disease, traffic jams in the cells control center kill brain cells date. N2 huntington s disease is an inherited, degenerative brain disease, characterized by involuntary movements, cognitive disorder and neuropsychiatric change. Content that exceeds the 3 page limit will not be graded. Inside the obriens by lisa genova, eternal on the water by joseph monninger, you me everything by catherine isaac. Huntingtons disease offers introduces this disease, detailing its history and progression, and discusses the search for the. Find comprehensive medical reference information including disease symptoms, diagnoses, treatments, and followup. Prevalence in the caucasian population is estimated at 110,0001. List of books and articles about huntingtons disease. Research databases huntington university, a christian. The disease affects muscle coordination, cognition and behavior. This bibliography was generated on cite this for me on thursday, may 12, 2016. Pdf huntington disease hd can be seen as a model neurodegenerative.
Popular huntington s disease books goodreads share book. Huntingtons disease other bibliographies cite this for me. This is a formal paper, formatted and referenced per apa guidelines. Huntington disease was formerly known as huntington chorea since the most obvious symptoms involve uncontrollable body movements known as chorea. In many areas, there are huntingtons disease clinics run by a specialist doctor and nurse, who can offer treatment and support and refer you to other specialists if needed. After huntingtons death, the new pastor of old south church, benjamin wisher, wrote a biography of her, including copious quotations from her letters and from her journal, which she kept for years. Clinical manifestations include chorea, cognitive decline, loss of coordination, and personality change. Apa style is the standard citation format for most social sciences, medical. Genetic modifier for huntingtons disease progression identified. It has a chapter about lyme disease that shows a very in depth look at the symptoms, and talks about some of the treatments. Present information in a scholarly manner clear, grammatically correct and reflect synthesis of information from sources. Huntington s disease is an autosomaldominant, progressive neurodegenerative disorder with a distinct phenotype, including chorea and dystonia, incoordination, cognitive decline, and behavioural difficulties.
Medline abstract for reference 32 of huntington disease. Oclcs webjunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus. In the united states alone, 1 in every 30,000 people has huntingtons disease genetic learning center. Au mestre t, ferreira j, coelho mm, rosa m, sampaio c so cochrane database syst rev. Juvenile huntington disease genetic and rare diseases nih. Designed for nursing students, the nursing resource center brings together in an easytouse interface disease and drug overviews, care plans, relevant journal results, and animated anatomy and physiology diagrams to complement the core encyclopedia texts. However, formatting rules can vary widely between applications and fields of interest or study. This page reflects the latest version of the apa publication manual i. Today, huntington s disease is treatable, but it is still a devastating disease that has no cure, but researchers are working on longterm treatment for the disease. The disease is sometimes confused with chorea or st.
Psychiatric management in neurological disease fills an important void in the practicing psychiatrists library. Jan 15, 2020 designed for nursing students, the nursing resource center brings together in an easytouse interface disease and drug overviews, care plans, relevant journal results, and animated anatomy and physiology diagrams to complement the core encyclopedia texts. This chapter will provide a brief background to huntingtons disease hd, before. Huntingtons disease, often abbreviated as hd, is a brain disease that causes nerve cells in the brain to deteriorate. A reference for the article on crohns disease in magills would look like this.
Research paper on huntingtons disease sample essays. Huntingtons disease is a multifaceted disease, with a complex inheritance pattern and a wide range of symptoms. Regional and cellular gene expression changes in human huntingtons disease brain. Huntingtons disease, variability and challenges for clinical neuropsychology. See the answer on how to cite a definition or entry from a reference book. This bibliography was generated on cite this for me on wednesday, february 17, 2016. Working with mouse, fly and human cells and tissue. Huntington disease hd is an autosomaldominant disorder, characterized as disease of progressive brain degeneration in late adulthood with subsequent brain atrophy. Huntingtons disease, hereditary, acute disturbance of the central nervous system usually beginning in middle age and characterized by involuntary muscular movements and progressive intellectual deterioration. This online article provides insight as to the origins of lyme disease. Although several drugs seem effective in controlling the incapacitating manifestations of hd, no specific therapy is known. May 16, 2018 huntington s disease is an inherited disease that causes the progressive breakdown degeneration of nerve cells in the brain.
Jul 01, 2008 huntington s disease, hereditary, acute disturbance of the central nervous system usually beginning in middle age and characterized by involuntary muscular movements and progressive intellectual deterioration. References for huntingtons disease biology bibliographies. People are born with the defective gene, but symptoms usually dont appear until middle age. The earliest symptoms are often subtle problems with mood or mental abilities. Find, read and cite all the research you need on researchgate. Huntington disease hd is a rare neurodegenerative disorder of the central nervous system characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia. George huntington originally discovered hd in 1872.
A general lack of coordination and an unsteady gait often follow. Huntingtons disease, or huntingtons chorea, is a progressive genetic disease marked by death of brain cells coupled with loss of muscular control and coordination, declining mental abilities, and erratic behavior. Huntingtons disease hd is an inherited disease that causes certain nerve cells in the brain to waste away. Huntington disease hd is a rare neurodegenerative disorder of the central nervous system characterized by unwanted choreatic movements, behavioral. Huntingtons disease, also known as huntingtons chorea, is a hereditary degenerative disorder of the central nervous system where the nerves become damaged and parts of the brain begin to deteriorate. It also may cause atrophy of the caudate nucleus, a part of the. Anxiety in huntingtons disease the journal of neuropsychiatry. It really serves to demonstrate how beneficial a good longitudinal study can be. Nance has written two books published by the huntington disease society of america about huntington disease hd, as well as several articles and book. The hereditary and debilitative nature of the disease means that many people are involved either directly or indirectly by this condition.
Huntington s disease has a broad impact on a persons functional abilities and usually results in movement, thinking cognitive and psychiatric disorders. Most people with huntington s disease develop signs and symptoms in their 30s or 40s, but the onset of disease may be earlier or later in life. Huntingtons disease hd, also known as huntingtons chorea, is an inherited disorder that results in the death of brain cells. Numerous and frequentlyupdated resource results are available from this search.
Food for huntingtons disease sultan qaboos university. Theres currently no cure for huntingtons disease or any way to stop it getting worse. This title also addresses the ethical questions of testing people for a disease whose symptoms typically develop later in life. Genetic modifier for huntingtons disease progression. Anxiety is common in huntingtons disease hd, though it has been. Clinical features and diagnosis 32 pubmed ti abnormal in vivo skeletal muscle energy metabolism in huntingtons disease and dentatorubropallidoluysian atrophy. Essay about huntingtons disease 1557 words bartleby. A novel gene containing a trinucleotide repeat that is unstable in huntingtons. Apr 25, 2019 huntington s disease hd is an inherited disease that causes certain nerve cells in the brain to waste away. George huntingtons on chorea inside huntingtons disease. Huntingtons disease is an autosomaldominant, progressive neurodegenerative disorder with a distinct phenotype, including chorea and dystonia, incoordination, cognitive decline, and behavioural difficulties. The affected areas of degeneration are the basal ganglia, which play an important role in the control of movement.
Huntington s disease can attack just about anyone, but it is involved in the genetics of a family. Apr 07, 2020 huntington s disease and laboratory investigation of this disease. Huntingtons disease can attack just about anyone, but it is involved in the genetics of a family. Background huntingtons disease hd is an autosomal dominant neurodegenerative disease with. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree. Huntingtons disease definition of huntingtons disease by. While the genetic basis of this lethal disease was identified more than two decades ago. Once you have the author, you can use the ebsco apa citation and add your extra information.
The book begins with an introductory chapter, which outlines the history of hd. About genetics home reference genetics home reference nih. If the nonmotor signs are less specific, it can be very difficult to make a diagnosis. Background huntington s disease hd is an autosomal dominant neurodegenerative disease with an average onset between the fourth and fifth decade of life. Hd was originally known as huntingtons chorea, coming from a greek word meaning to dance, which describes some symptoms of hd. Molecular and cellular pathobiology and prospects for prevention, diagnosis and treatment. Use apa format for headings, citations and references. Ama apa 6th edition apa 7th edition chicago 17th edition. Such changes, unlike chorea, directly impair function, a finding that is, in part, indicated by the modern preference for the terminology huntingtons disease rather than huntingtons chorea. Today, huntingtons disease is treatable, but it is still a devastating disease that has no cure, but researchers are working on longterm treatment for the disease. The first definite mention of hd was in a letter by charles oscar waters. An online reference service made up of fulltext books from the worlds best publishers individual titles are listed in the catalog. Huntington s disease is a hereditary brain disorder that is progressive in neurodegeneration. Drawing on the expertise of key researchers in the field, the book discusses the basic neurobiology of huntingtons disease.
Huntington published a few poems in the boston recorder. Neurobiology of huntingtons disease ncbi bookshelf. Whether you have a big paper due for class or are about to publish a study, making sure your quotes are properly cited is important. Huntingtons disease is an autosomal dominant neurodegenerative disorder. How to i create an apa reference for magills medical guide. Essay huntington s disease huntington s disease, or huntngtons chorea, is a genetic disease that causes selective neural cell death, which results in chorea, or irregular, jerking movements of the limbs caused by involuntary muscle contractions, and dementia. Apr 17, 2017 reference styles such as american psychological association and modern language association include special rules for referencing publications by government agencies such as the cdc. But treatment and support can help reduce some of the problems caused by the condition. This publication provides insight as to the diagnosis process of lyme disease. This chapter will provide a brief background to huntingtons disease hd. Huntingtons disease has a broad impact on a persons functional abilities and usually results in. Huntingtons disease affects movement, behavior and cognition of the individual and his or her ability to walk, think and reason. Apa psychiatric management in neurological disease. Management 63 pubmed ti therapeutic interventions for disease progression in huntingtons disease.
In the long run it results in the loss of both mental and physical control. These are the sources and citations used to research huntington s disease. Find articles nursing libguides at huntington university. Symptoms emerge at around 40 years, although there is wide variation. Cite your book in american psychological association 6th edition format for free. Early english books online trial through december 6, 2014. Early signs and symptoms can include irritability, depression, small involuntary. Huntingtons disease is a disease that is passed from generation to generation and. The equivalent resource for the older apa 6 style can be found here. S i want to do huntington disease as my genetic topic. Huntington s disease is an autosomal dominant neurodegenerative disorder. However, it remains unclear whether psychiatric changes in the preclinical period result from structural change, are a reaction to being at risk or simply a coincidental occurrence. Huntingtons disease hd, also known as huntingtons chorea, is an inherited disorder that. Typically, onset of symptoms is in middleage after affected individuals have had children, but the disorder can manifest at any time between infancy and.
The website provides information for the general public about the effects of genetic variation on human health. Such changes, unlike chorea, directly impair function, a finding that is, in part, indicated by the modern preference for the terminology huntington s disease rather than huntington s chorea. Oclcs webjunction has pulled together information and resources to assist library staff as they consider how to handle. Often presents in midlife but may appear at any age. Huntingtons disease is a genetically inherited condition which results in severe nervecell damage in the brain. In huntingtons disease, traffic jams in the cells control center kill brain cells date.
167 264 112 200 708 2 950 627 1131 82 287 927 685 864 1384 188 684 1365 1279 1301 652 1365 1476 299 236 145 878 405 756 635 1189 880